this is the serological data. The serological measurements are bivariate. That is, y = (igg, igm), and each of igg and igm are taken at 6 time points. IGG0 = igg measurement at day 0 IGG28 = igg measurement at day 28 IGM42 = igm measurement at day 42 and so on IGGrel = IGG measurement at time of relapse IGMrel= IGM measurement at time of relapse --------------------------------------- CASE TRT IGG0 IGG28 IGG42 IGG84 IGG364 IGGrel IGM0 IGM28 IGM42 IGM84 IGM364 IGMrel 26001 B 0 20 640 80 80 . 0 40 160 20 0 . 26002 B 0 0 0 0 0 . 0 320 320 80 0 . 26003 A 0 80 80 320 . . 0 1280 640 640 . . 26004 A 0 0 0 0 80 . 0 40 80 0 0 . 26005 C 0 20 0 0 . . 0 1280 640 640 . . 26006 C 0 160 80 40 640 . 0 160 80 0 0 . 26007 C 0 0 0 0 . . 0 0 20 20 . . 26008 A 0 20 80 160 80 . 160 2560 2560 640 80 . 26009 B 0 20 80 0 1280 . 0 80 160 40 640 . 26010 B 0 640 . . . . 0 320 . . . . 26011 A 0 40 40 160 . 5120 0 160 40 0 . 40 26012 B 0 0 0 0 . 0 0 40 80 0 . 0 26013 C 0 0 160 0 . 0 0 1280 1280 160 . 320 26014 C 0 0 0 0 80 . 0 0 0 0 0 . 26015 C 0 20 40 80 640 . 0 160 80 80 0 . 26016 A 0 0 0 0 2560 . 0 80 0 0 160 . 26017 A . 80 320 320 . . . 160 2560 640 . . 26018 B 0 0 160 0 . . 0 0 160 0 . . 26019 B 0 0 160 40 . . 0 20 80 0 . . 26020 A 0 80 40 20 . 40 0 640 320 40 . 40 26021 C 0 40 160 . . 0 0 160 160 . . 0 26022 A 0 0 . 0 160 . 0 0 . 0 0 . 26023 B 0 2560 10240 5120 2560 . 0 40 320 80 0 . 26024 C 0 0 160 20 . . 0 160 160 40 . . 26025 A 0 40 80 40 . . 0 80 40 20 . . 26026 B 0 0 80 40 1280 . 0 80 40 20 640 . 26027 A 0 0 80 0 . . 0 40 0 0 . . 26028 C . 0 0 0 . . . 320 160 40 . . 26029 C 0 0 0 . . . 0 1280 80 . . . 26030 B 0 40 80 20 . . 0 1280 1280 640 . . 26031 C 0 0 0 40 320 . 20 160 40 80 0 . 26032 C 0 0 40 0 . 80 0 160 320 80 . 160 26033 B 0 40 . . . . 0 320 . . . . 26035 B 0 40 40 40 640 . 0 2560 2560 320 320 . 26036 A 0 0 40 0 160 . 0 160 640 80 80 . 26037 C 0 80 80 80 . . 0 640 1280 320 . . 26038 A 0 0 0 20 80 . 0 160 80 20 0 . 26039 C 0 0 0 0 . . 0 160 80 40 . . 26040 A 0 80 160 80 80 . 0 320 320 160 80 . 26041 B 0 . 80 80 320 . 0 . 160 40 80 . 26042 B 0 160 160 80 1280 . 0 1280 2560 640 160 . 26043 B 0 80 320 160 10240 . 0 160 320 20 40 . 26044 C . 0 0 0 . 0 . 0 40 0 . 0 26045 B 0 0 40 0 5120 . 0 160 640 40 320 . 26046 C 0 0 40 40 1280 . 0 160 160 80 640 . 26047 A 0 0 0 20 160 . 0 640 1280 160 80 . 26048 A 0 40 640 160 1280 . 0 640 640 640 40 . 26049 C 0 0 40 0 1280 . 0 40 40 20 0 . 26050 A 0 0 . . . . 0 40 . . . . 26051 B 0 20 80 40 40 . 80 1280 640 160 160 . 26052 A 0 0 0 0 2560 . 0 160 640 160 640 . 26053 B 0 1280 160 320 1280 . 0 640 160 40 320 . 26054 C 0 0 0 0 80 . 0 320 320 160 160 . 26055 A 0 . 640 320 1280 . 0 . 320 40 160 . 26056 A 0 0 160 40 640 . 0 160 1280 160 0 . 26057 C 0 40 320 320 640 . 0 320 320 320 160 . 26058 B 0 0 . . . . 0 80 . . . . 26059 B 0 80 160 160 2560 . 0 1280 1280 640 160 . 26060 C 0 . 640 . 0 . . . 80 . 0 . 26062 B . 0 320 80 320 . . 320 160 40 40 . 26063 C 0 0 80 20 80 . 0 80 80 40 40 . 26064 A 0 0 160 40 320 . 0 640 2560 320 0 . 26065 C 0 1280 2560 1280 1280 . 20 2560 640 320 160 . 26066 B 0 80 320 40 640 . 0 320 320 40 0 . 26067 A 0 0 0 20 2560 . 0 640 2560 640 80 . 26068 A 0 0 0 20 320 . 0 80 40 0 0 . 26069 C 0 320 640 320 1280 . 0 1280 2560 1280 320 . 26070 C 0 20 40 20 . 80 0 320 160 80 . 80 26071 B . 20 80 20 . . . 160 80 40 . . 26072 A 0 0 0 40 . 640 0 320 640 160 . 0 26073 A 0 0 160 40 640 . 0 160 80 80 80 . 26074 C 0 20 80 20 80 . 0 80 80 80 40 . 26075 C 0 160 640 640 1280 . 0 160 640 320 320 . 26076 A 0 . 0 20 160 . 0 . 160 20 0 . 26077 B 0 160 . 80 10240 . 0 2560 . 1280 640 . 26078 B 0 1280 160 160 . . 0 20 0 0 . . 26079 C . . 0 0 640 . . . 160 40 0 . 26080 A . 80 80 80 . . . 80 80 80 . . 26081 A 0 . . 0 640 . 0 . . 0 0 . 26082 B 0 160 160 160 10240 . 0 1280 640 160 160 . 26083 A . 0 0 0 0 . . 80 80 80 0 . 26084 C . 0 40 0 1280 . . 640 320 80 80 . 26085 B 0 0 0 . . . 0 160 80 . . . 26086 C 0 20 40 0 1280 . 0 80 40 0 40 . 26087 A 0 0 640 80 . . 0 640 640 40 . . 26088 A 0 0 320 40 2560 . 0 40 40 0 0 . 26089 C . 0 0 . . . . 160 80 . . . 26090 C . 40 80 40 . . . 80 160 40 . . 26091 B 0 0 . 0 1280 . 0 0 . 0 0 . 26092 B 0 0 40 0 . 0 0 320 160 40 . 0 26093 B 0 40 80 0 . . 0 640 160 0 . . 26094 C . 80 40 0 80 . . 320 160 320 80 . 26095 A . 20 80 0 640 . . 160 80 40 80 . 26096 A 0 20 160 80 640 . 0 320 160 80 0 . 26097 C 0 160 160 . 2560 . 0 1280 640 . 40 . 26098 B 0 40 40 . 1280 . 0 80 80 . 0 . 26099 B 0 80 0 0 80 . 0 80 40 0 0 . 26100 A 0 40 320 320 1280 . 0 160 320 40 0 . 26101 A 0 0 0 80 . . 0 20 320 160 . . 26102 C 0 320 0 40 . . 0 20 160 0 . . 26103 A 0 . 0 . 80 . 0 . 0 . 0 . 26104 C 0 80 80 . . . 0 160 160 . . . 26105 B 0 0 0 0 5120 . 0 160 40 0 160 . 26106 B 0 0 640 320 2560 . 0 80 1280 160 40 . 26107 A 0 0 0 0 0 . 0 80 640 0 0 .